Clinical trial · Interventional
Resistance Exercise Training for the Shoulder and Neck Following Surgery for Head and Neck Cancer
Randomized Controlled Trial of Progressive Resistance Exercise Training for Spinal Accessory Neurapraxia/ Neurectomy in Head and Neck Cancer Survivors
NCT00248235CI-TRIAL-00082212completedPhase 2 / Phase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to investigate the effect of a progressive therapeutic exercise program on specific physical and functional deficits in the neck and shoulder region occurring as a result of head and neck cancer treatment.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Neoplasms | Head and Neck Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Exercise | Behavioral | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- PRET
- description
- Progressive Resistance Exercise Training: upper extremity 6-8 exercises
- interventionNames
- Behavioral: Exercise
- type
- ACTIVE_COMPARATOR
- label
- Standard Care
- description
- Standard Care: physical therapy - range of motion, 6-8 strengthening exercises
- interventionNames
- Behavioral: Exercise
Primary outcomes (4)
- measure
- Pain and dysfunction (baseline, 12 weeks, 6 months, 12 months)
- timeFrame
- baseline, 12 weeks, 6 months, 12 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Squamous cell carcinoma of the oral cavity, oropharynx, larynx or hypopharynx OR squamous cell carcinoma metastatic to the neck from unknown primary site; probable occult mucosal origin in the head and neck 2. Surgical treatment includes radical neck dissection, modified radical neck dissection and other variants of functional/selective neck dissection 3. Karnofsky Performance Status greater than or equal to 60% 4. No evidence of residual cancer in the neck and no distant (M0) metastasis 5. Participants must have completed their head and neck cancer treatment Exclusion Criteria: 1. A history of shoulder or neck pathology unrelated to cancer treatment 2. Serious co-morbid medical illness or psychiatric illness
References
Publications (1)
- BACKGROUNDMcNeely ML, Parliament M, Courneya KS, Seikaly H, Jha N, Scrimger R, Hanson J. A pilot study of a randomized controlled trial to evaluate the effects of progressive resistance exercise training on shoulder dysfunction caused by spinal accessory neurapraxia/neurectomy in head and neck cancer survivors. Head Neck. 2004 Jun;26(6):518-30. doi: 10.1002/hed.20010. PMID 15162353