Clinical trial · Interventional
Endometrial Polyps: Pathophysiology and Clinical Consequences
Endometrial Polyps. Pathophysiology and Clinical Consequences.
NCT00247923CI-TRIAL-00005173completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The aim of these studies is to study the natural history, the symptoms of, as well as the effect of hysteroscopic resection of endometrial polyps. Furthermore, another aim is to study new diagnostic techniques to differentiate between malignant and benign endometrial polyps.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
| Endometrial Polyp | Endometrial Polyp | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Hysteroscopic resection of endometrial polyps. (TCRP) | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (4)
- measure
- Study part 1. Angiogenesis factor levels in endometrial biopsies in patients with endometrial polyps compared to patients with endometrial cancer
- measure
- Resistance in the feeding vessel measured by doppler examination combined with intravenous (i.v.) contrast in patients with endometrial polyps and endometrial cancer
- measure
- Study part 2. Change in pictorial blood loss assessment chart (PBAC) score in intervention compared to observation group
- measure
- Study part 3. Change in PBAC score in women with endometrial polyps compared to control group
Secondary outcomes (2)
- measure
- Associated factors for the development of endometrial polyps
- measure
- Change in endometrial polyp size and symptoms after 6 and 12 months of observation
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 16 Years
- Maximum age
- 90 Years
Show eligibility criteria text
Inclusion Criteria: * Study 1: * Endometrial polyp (EP) group: Presence of endometrial polyp verified by vaginal ultrasound examination. * Cancer group: Presence of endometrial cancer verified by histological examination. * Study 2: * Pre- or perimenopausal women. * Presence of endometrial polyp verified by vaginal ultrasound. * Study 3: * EP group: Presence of endometrial polyp verified by vaginal ultrasound. * Control group: Normal endometrium by vaginal ultrasound examination. Exclusion Criteria: * Study 1: Earlier severe allergic reactions. * Study 2: * Postmenopausal patient. * Pregnancy. * Additional condition requiring treatment detected during examination. Malignancy or atypical hyperplasia detected by histological examination. * Study 3: * Previous hysterectomy. * Pregnancy. * Additional condition requiring treatment detected during examination. Malignancy or atypical hyperplasia detected by histological examination.
References
Publications (0)
Data not yet available
No reference posted for this study.