Clinical trial · Interventional

Debulking Effect of Curretage on Basal Cell Carcinomas - a Histological Assessment.

Relation of Basal Cell Carcinoma Tumour Thickness, Histologically Estimated, in Punch Biopsies Performed Before and After Curretage.

NCT00237107CI-TRIAL-00023142completedN/AClinicalTrials.gov clinicaltrialsPublishedExplore in graph →

Summary

Brief summary (as posted)

The aim of this study was to compare histologically observed tumour infitration of basal cell carcinoma (bcc) lesions before and after curretage.A significant reduction of tumour depth would enable further bcc's included for superficial non-invasive treatment modalities such as topical photodynamic therapy.

Conditions

Conditions (1)

Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.

Condition (as posted)	Mapped entity	Match	Confidence
Carcinoma, Basal Cell	Basal Cell Carcinoma	ONTOLOGY_EXACT	0.90

Interventions

Interventions (1)

Intervention	Type	Mapped drug	Match
Curretage	Procedure	—	UNRESOLVED

Design

Arms and outcomes

Arms (1)

type
EXPERIMENTAL
label
curettage
interventionNames
1. Procedure: Curretage

Primary outcomes (1)

measure
Reduction of tumour thickness 0,5mm or more after curretage
timeFrame
1 hour

Secondary outcomes (1)

measure
Comparison of tumour thickness in punch biopsies performed on referral, before and after curretage.
timeFrame
3 months

Eligibility

Eligibility (as posted)

Sex: All
Minimum age: 18 Years

Show eligibility criteria text

Inclusion Criteria:

* bcc with tumour depth two mm.or more

Exclusion Criteria:

* bcc tumours smaller than three mm in mean diameter.

References

Publications (1)

RESULTChristensen E, Mork C, Foss OA. Pre-treatment deep curettage can significantly reduce tumour thickness in thick Basal cell carcinoma while maintaining a favourable cosmetic outcome when used in combination with topical photodynamic therapy. J Skin Cancer. 2011;2011:240340. doi: 10.1155/2011/240340. Epub 2011 Nov 15. PMID 22191035