Clinical trial · Interventional
A Feasibility Study of Smoking Cessation Program in Radiation Oncology
NCT00236288CI-TRIAL-00000932completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To test the feasibility of an intensive behavioral and pharmacologic tobacco cessation program for radiation oncology patients and their families/companions.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Cancer and Tobacco Abuse | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Bupropion and intensive behavioral therapy | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To test the feasibility of using the medication bupropion and behavioral therapy to help people stop smoking in the radiation oncology clinic.
- timeFrame
- 1 year from enrollment
Secondary outcomes (1)
- measure
- Smoking cessation status will be formally assessed by patient report, and for those reporting tobacco abstinence, confirmed by carbon monoxide breath testing concentrations of 10 ppm or less.
- timeFrame
- 1 year from enrollment
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Eligibility for Radiotherapy Patients * age 18 years or older * receiving three weeks or more of external beam radiotherapy * report smoking one or more cigarettes in the past 30 days or self-identify as a smoker * Cancer Stage: * Stage I-III * IVa Head and Neck Malignancy is allowed * Stage I-IV breast, prostate, testis or lymphoma also allowed * at least one year life expectancy * have given written informed consent * KPS 70-100 Eligibility for Family/Companions of Radiotherapy Patients (Note: Family members/companions are eligible for this protocol regardless of whether the index radiotherapy patient is eligible or willing to participate.) * age 18 years or older * at least one year life expectancy * radiotherapy patient is receiving three weeks or more of external beam radiotherapy * Person is committed to bringing/accompanying the patient to radiotherapy at least three days per week. * report smoking one or more cigarettes in the past 30 days or self-identify as a smoker * Family member/companion of patients under radiotherapy treatment for any stage of cancer * have given written informed consent * KPS 70-100 Exclusion Criteria: * Exclusion Criteria for both Radiotherapy Patients and their Families/Companions * serious or unstable cardiac, renal, hypertensive, pulmonary, endocrine, or neurologic disorders, as assessed by the study-site physician * a current diagnosis of major depressive episode or a history of panic disorder, psychosis, bipolar disorder, or eating disorders * pregnancy or lactation * any history of allergy/intolerance or adverse reaction to bupropion * history of seizure disorder, bulimia or anorexia nervosa * use of an MAOi within 14 days * current use of another antidepressant * abrupt discontinuation of alcohol or sedatives * unwilling/unable to meet with the behavioral interventionalist for 20 minutes, at least 3 days per week during the course of radiotherapy
References
Publications (0)
Data not yet available
No reference posted for this study.