Clinical trial · Interventional
Radiofrequency of Breast Cancers in Non Surgical Patients
Radiofrequency of Breast Cancers : Pilot Study in Non Surgical Patients
NCT00210223CI-TRIAL-00096058RF-SEINcompletedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
To determine the efficacy and tolerance of ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy in elderly patients with breast cancer who decline or are not candidates for surgery.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- US-RF + endocrine therapy
- description
- ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy
- interventionNames
- Procedure: ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy
Primary outcomes (1)
- measure
- Number of Participants With Disease Recurrence One Year After the Intervention.
- timeFrame
- one year
- description
- The intervention was ultrasonography (US)-guided percutaneous radiofrequency (RF) ablation with endocrine therapy. Recurrence was assessed based on follow-up with dynamic contrast material-enhanced (DCE) magnetic resonance (MR) imaging).
Secondary outcomes (1)
- measure
- Number of Participants With Disease Recurrence at 5 Years
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion criteria: * Patients more than 70 years old * Breast tumors with estrogen receptors * Non surgical patients * Life expectancy more than 6 months Exclusion criteria: * Presence of a pace maker * Tumors measuring more than 30 mm on ultrasound evaluation, located less than 10 mm from skin, nipple, or pectoral muscle * Coagulation disorders * Contra indications to magnetic resonance imaging or computed tomography with contrast medium injection * Non visible lesions on magnetic resonance imaging or computed tomography with contrast medium injection
References
Publications (1)
- BACKGROUNDPalussiere J, Henriques C, Mauriac L, Asad-Syed M, Valentin F, Brouste V, Mathoulin-Pelissier S, Tunon de Lara C, Debled M. Radiofrequency ablation as a substitute for surgery in elderly patients with nonresected breast cancer: pilot study with long-term outcomes. Radiology. 2012 Aug;264(2):597-605. doi: 10.1148/radiol.12111303. Epub 2012 Jun 12. PMID 22692040