Clinical trial · Interventional
Weekly Topotecan in the Second-Line Treatment of Small Cell Lung Cancer
Phase II Trial of Weekly Topotecan in the Second-Line Treatment of Small Cell Lung Cancer
NCT00193388CI-TRIAL-00003723completedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
In this phase II trial, we will evaluate the weekly schedule of topotecan in the second-line treatment of patients with small cell lung cancer
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Lung Cancer | Malignant Lung Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Topotecan | Drug | Topotecan | ALIAS |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Overall response rate
Secondary outcomes (3)
- measure
- Median survival
- measure
- 1-year survival
- measure
- Symptomatic improvement
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: To be included in this study, you must meet the following criteria: * Small Cell Lung cancer * Progression after one previous regimen * Measurable or evaluable disease * Able to perform activities of daily living with assistance * Adequate bone marrow, liver and kidney function * No more than three previous courses of radiation therapy * Accessible for treatment and follow up * Must give written informed consent prior to study entry Exclusion Criteria: You cannot participate in this study if any of the following apply to you: * Central nervous system involvement * Serious or active infection * Serious underlying medical condition * Other active neoplasms Please note: There are additional inclusion/exclusion criteria. The study center will determine if you meet all of the criteria. If you do not qualify for the trial, study personnel will explain the reasons. If you do qualify, study personnel will explain the trial in detail and answer any questions you may have.
References
Publications (0)
Data not yet available
No reference posted for this study.