Clinical trial · Interventional
Study of Breath-holding as a Means to Reduce Tumor Motion From Breathing
Feasibility Study for Gated External-Beam Radiotherapy for Patients With Internal, Extra-cranial Tumors
NCT00178477CI-TRIAL-00010086terminatedN/AResults postedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Drs Okunieff and ODell have left the University of Rochester
Summary
Brief summary (as posted)
The purpose of this research study is to evaluate typical tumor motion caused by breathing using MRI and can help determine whether simple passive breathing and/or breath-holding could be used for the future treatment of similar lung and liver tumors using radiation therapy radiosurgery techniques.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasm, Metastatic | Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI with breath-holding | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Breath-holding
- description
- MRI with breath-holding
- interventionNames
- Procedure: MRI with breath-holding
Primary outcomes (1)
- measure
- Tumor Motion Related to Breathing as Determined From MRI Images
- timeFrame
- 20 - 30 seconds
- description
- 1. Determine the typical and maximal tumor 3D displacements over the respiratory cycle and how these values vary depending on the tumor location 2. Determine the reproducibility of target position over multiple breath-holds 3. Determine the variability across patients in respiratory-derived lesion motion and target position reproducibility over multiple breath-holds
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * The patient is enrolled on U8700 RSRB # A Phase II Study For Using Radiosurgery On Limited Metastases Of Breast Cancer or U9700 A Pilot Study For Using Radiosurgery On Limited Metastases. * ≥ 18 years of age * has given Informed consent Exclusion Criteria: -Contraindications for any MRI procedure
References
Publications (0)
Data not yet available
No reference posted for this study.