Clinical trial · Observational
Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury
NCT00178295CI-TRIAL-00018770completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Treatment for brain cancer may include radiation therapy. Radiation therapy is the treatment of tumors with X-rays. This study is related to understanding the side effects of radiation treatment for brain tumors. This study is being conducted by the University of Rochester Cancer Center to compare the extent of side effects of brain cancer treatment with changes in levels of blood proteins called cytokines.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Neoplasm | Brain Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Radiation Therapy | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Change from baseline in Cytokine blood levels
- timeFrame
- 12 weeks from start of radiation
Eligibility
Eligibility (as posted)
- Sex
- All
Show eligibility criteria text
Inclusion Criteria: * Any patient who will be treated to the brain or spinal axis for a CNS tum Patients so treated will be stratified according to whether or not the hypo is included in the treatment fields. * Patients receiving external beam radiation to the brain may also be rece chemotherapy or interferon-beta. (Add. #1, 11-9-95) * Patients receiving high dose rate (stereotactic radiosurgery) are eligible. * Patients must sign a study specific informed consent meeting all federal a guidelines. * Patients of any age, including children, are eligible (Add. #3, 11/25/97). Exclusion Criteria: * Patients who have a malignancy involving the hypothalamic-pituitary ax * Patients who are not treated with irradiation to the brain or spinal axis.
References
Publications (0)
Data not yet available
No reference posted for this study.