Clinical trial · Interventional
Drainage of Malignant Extrinsic Ureteral Obstruction Using the Memokath Ureteral Stent
Long-Term Temporary Drainage of Malignant Extrinsic Ureteral Obstruction Secondary to Inoperable Pelvic or Abdominal Malignancies Using the Memokath 051 Ureteral Stent
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate the safety and efficacy of the Memokath 051 ureteral stent as a long-term temporary and minimally invasive means of providing ureteral drainage in the setting of malignant extrinsic ureteral obstruction secondary to inoperable abdominal or pelvic malignancies. Up to 15 adults who have extrinsic ureteral obstruction secondary to an inoperable abdominal or pelvic malignancy and need ureteral stent drainage will undergo outpatient placement of the ureteral stent. Ongoing monitoring will continue for as long as the stent is in place.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Ureteral Obstruction | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| JJ Stent | Device | — | UNRESOLVED |
| Memokath 051 Ureteral Stent | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Memokath 051 Ureteral Stent
- description
- Subjects assigned to this arm received a Memokath 051 Ureteral Stent.
- interventionNames
- Device: Memokath 051 Ureteral Stent
- type
- ACTIVE_COMPARATOR
- label
- JJ Stent
- description
- Subjects assigned to this arm received a JJ stent.
- interventionNames
- Device: JJ Stent
Primary outcomes (1)
- measure
- Mean Stent Dwell Time
- timeFrame
- baseline to 59 months after placement of stent
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Presence of extrinsic ureteral obstruction 1. secondary to inoperable pelvic or abdominal malignancy or 2. secondary to changes caused by surgery, chemotherapy, or radiation for pelvic and/or abdominal malignancies who have had \>2 standard double J stent exchanges with no prospect of being stent-free 2. Life expectancy greater than 4 months 3. Adult patient (18 years of age or older) 4. Preoperative medical examination clearing the patient for general anesthesia 5. No active urinary tract infection by urinalysis and urine culture. Exclusion Criteria: 1. Ureteral obstruction of a benign or intrinsic etiology 2. Lower urinary tract abnormality precluding cystoscopic stent placement 3. Patients with a solitary kidney 4. Patients not willing or unable to receive their post-operative follow-up at the Mayo Clinic in Rochester, Minnesota 5. Pregnant female patient.
References
Publications (0)
Data not yet available