Clinical trial · Interventional
Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer
Tangential Radiation Therapy Without Axillary Dissection in Early-Stage Breast Cancer
NCT00165243CI-TRIAL-00028015completedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to evaluate whether treatment to the axilla (area under the arm) can be safely minimized by omitting axillary surgery and full axillary radiation therapy and replacing it with radiation therapy to the breast and lower axilla.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Early-Stage Breast Cancer | Early Stage Breast Carcinoma | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Tangential radiation | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- To determine if patients with early-stage breast tumors can be effectively treated by tangential breast radiation.
- timeFrame
- 5 years
Secondary outcomes (1)
- measure
- To determine the safety of this treatment.
- timeFrame
- 5 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 55 Years
Show eligibility criteria text
Inclusion Criteria: * Patients must have clinical stage I or II breast cancer, clinically uninvolved axillary nodes. * Patients must be 55 years or older. * Patients must undergo total excision of the primary invasive tumor * Final pathologic margin status must be negative * Only estrogen receptor (ER) or progesterone receptor (PR) positive tumors will be permitted Exclusion Criteria: * Prior history of malignancy, except for non-melanoma skin cancers and carcinoma in situ fo the cervix
References
Publications (0)
Data not yet available
No reference posted for this study.