Clinical trial · Interventional
Effect of Iron and Vitamin E Supplementation on Disease Activity in Patients With Either Crohn's Disease or Ulcerative Colitis
Effect of Iron and Antioxidant Vitamins on Disease Activity and Oxidative Stress in Inflammatory Bowel Disease (IBD)
NCT00152841CI-TRIAL-00002133terminatedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Lack of patients
Summary
Brief summary (as posted)
Hypothesis:In patients with ulcerative colitis and Crohn's disease diagnosed with mild or moderate anaemia: 1. iron supplementation will increase disease activity and oxidative stress 2. the addition of antioxidant vitamin will reduce this detrimental effect
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Crohn's Disease | — | UNRESOLVED | — |
| Mild or Moderate Anaemia | — | UNRESOLVED | — |
| Ulcerative Colitis | — | UNRESOLVED | — |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Iron supplement 300-600 mg/day | Drug | — | UNRESOLVED |
| Vitamin E 800IU | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- calprotectin in stools at baseline, week 4, week 6, week 10
Secondary outcomes (4)
- measure
- disease activity index
- measure
- oxidative stress (plasma lipid peroxides, antioxidant potency, vitamin C, vitamin E, superoxide dismutase)
- measure
- blood measurement of CBD
- measure
- iron status
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * \> 18 years old * diagnosed with inflammatory Bowel Disease (ulcerative colitis and Crohn's disease) * with mild or moderate anaemia Exclusion Criteria: * not diagnosed with bowel obstruction * not diagnosed with short bowel syndrome * not taking iron supplement or antioxidant vitamins and minerals
References
Publications (0)
Data not yet available
No reference posted for this study.