Clinical trial · Interventional
Trial of Five Versus Six Fractions Per Week for Head and Neck Cancer
Phase III Trial of Five Versus Six Fractions Per Week for Head and Neck Cancer
NCT00120211CI-TRIAL-00005626completedPhase 3ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This trial compares the use of 6 fractions versus the standard 5 fractions of radiotherapy used in the treatment of head and neck cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Accelerated Radiotherapy Fractionation | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Radiotherapy: 6 Fractions
- interventionNames
- Radiation: Accelerated Radiotherapy Fractionation
- type
- ACTIVE_COMPARATOR
- label
- Radiotherapy: 5 fractions
- interventionNames
- Radiation: Accelerated Radiotherapy Fractionation
Primary outcomes (1)
- measure
- Three Years Loco-regional Control
- timeFrame
- 3 years
Secondary outcomes (4)
- measure
- Disease-specific Survival
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Head and Neck Cancer Exclusion Criteria: * Unable to give an informed consent
References
Publications (1)
- DERIVEDOvergaard J, Mohanti BK, Begum N, Ali R, Agarwal JP, Kuddu M, Bhasker S, Tatsuzaki H, Grau C. Five versus six fractions of radiotherapy per week for squamous-cell carcinoma of the head and neck (IAEA-ACC study): a randomised, multicentre trial. Lancet Oncol. 2010 Jun;11(6):553-60. doi: 10.1016/S1470-2045(10)70072-3. Epub 2010 Apr 8. PMID 20382075