Study of Pemetrexed in the Treatment of Patients With Ovarian Cancer Who Have Failed Prior Platinum-Based Chemotherapy

Inclusion Criteria:

* Patient must have been diagnosed with ovarian or primary peritoneal cancer
* Patient must have had 1 or 2 prior platinum-based chemotherapeutic regimens.
* Patient must have adequate health status.
* Patient compliance and geographic proximity that allow for adequate follow up is required.
* Signed informed consent from the patient or legal representative is required.

Exclusion Criteria:

* Patient is pregnant or breast-feeding
* Patient has received treatment within the last 30 days with a drug that has not received regulatory approval for any indication at the time of study entry.
* Patient has previously participated in another study investigating pemetrexed.
* Patient is unable or unwilling to take folic acid, vitamin B12 supplementation, and corticosteroids.
* Patient cannot be taking nonsteroidal anti-inflammatory drugs around the time of administration of study drug.