Clinical trial · Interventional
Initial Safety Assessment of SNS-595 for the Treatment of Solid Tumors.
Phase I Open-Label, Multicenter, Dose-Escalation Clinical Study of the Initial Safety and Pharmacokinetic Profiles of Intravenous Administration of SNS-595 in Patients With Advanced Malignancies
NCT00091585CI-TRIAL-00000725completedPhase 1ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The purpose of this study is to determine whether SNS-595 given intravenously once every 3 weeks is safe.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| SNS-595 | Drug | — | UNRESOLVED |
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Must give written informed consent * 18 years of age * Advanced solid malignant tumors * Tumor can be measured and evaluated * Blood tests are within standard limits * Normal blood coagulation * ECOG Performance Status equal to 0 or 1 Exclusion Criteria: * Pregnant or breastfeeding. * Women of childbearing potential unwilling to use an approved, effective means of contraception according to the institution's standards. * Heart attack, stroke/TIA or other blood clotting event (deep vein thrombosis or pulmonary embolus) within 6 months before the screen visit. * Requires kidney dialysis (hemodialysis or peritoneal). * Known bleeding disorder (ie, hemophilia, von Willebrand Disease, coagulopathy, etc.). * Received an investigational agent or prior chemotherapy or immunotherapy within 28 days before first dose of SNS-595 * Receiving therapeutic anticoagulation therapy (coumadin, heparin, etc.). * Currently receiving corticosteroids (inhaled steroids for breathing diseases are allowed) or seizure medications. * Any medical, psychological, or social condition that, in the opinion of the Principal Investigator, would contraindicate the patient's participation in the clinical trial due to safety and or compliance with study procedures.
References
Publications (0)
Data not yet available
No reference posted for this study.