Clinical trial · Interventional
Genetic and Environmental Risk Assessment for Colorectal Cancer in Healthy Participants
Providing Genetic And Environmental Cancer Risk Assessment In Primary Care
NCT00087360CI-TRIAL-00011324completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Evaluating the knowledge and attitudes of healthy participants toward a new diet and gene test for colorectal cancer risk may help doctors improve acceptance of colorectal cancer screening. PURPOSE: This clinical trial is studying the knowledge and attitudes of healthy participants toward genetic and environmental risk assessment for colorectal cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| counseling intervention | Other | — | UNRESOLVED |
| evaluation of cancer risk factors | Procedure | — | UNRESOLVED |
| physiologic testing | Other | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Colorectal cancer (CRC) screening rates by chart review at 4 months
Secondary outcomes (2)
- measure
- Knowledge regarding CRC risk by questionnaires at 4 and 12 months
- measure
- CRC risk perception by questionnaires at 4 and 12 months
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 50 Years
- Maximum age
- 74 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS:
* Healthy participants
* Eligible for colorectal cancer screening
* No personal or family history of colorectal cancer
* No more than 1 first-degree relative who has had colorectal cancer
* Part 1:
* Has not undergone regular screening for colorectal cancer
* Part 2:
* Not currently undergoing regular colon cancer testing, including any of the following:
* Fecal occult blood testing within the past year
* Flexible sigmoidoscopy or colonoscopy within the past 5 years
PATIENT CHARACTERISTICS:
Age
* 50 to 74
Performance status
* Not specified
Life expectancy
* Not specified
Hematopoietic
* Not specified
Hepatic
* Not specified
Renal
* Not specified
Other
* No inflammatory bowel disease (part 1 only)
* No concurrent health issues that would preclude study participation (part 1 only)
* No history of cancer except basal cell or squamous cell skin cancer (part 2 only)
* Able to speak and read English (part 2 only)
PRIOR CONCURRENT THERAPY:
Biologic therapy
* Not specified
Chemotherapy
* Not specified
Endocrine therapy
* Not specified
Radiotherapy
* Not specified
Surgery
* Not specifiedReferences
Publications (1)
- DERIVEDWeinberg DS, Myers RE, Keenan E, Ruth K, Sifri R, Ziring B, Ross E, Manne SL. Genetic and environmental risk assessment and colorectal cancer screening in an average-risk population: a randomized trial. Ann Intern Med. 2014 Oct 21;161(8):537-45. doi: 10.7326/M14-0765. PMID 25329201