Clinical trial · Observational
Genetic Study of Familial Factors in Patients With Colon Cancer
Familial Factors in the Development of Colon Cancer
NCT00055848CI-TRIAL-00023015completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Genetic studies may help in understanding the genetic processes involved in the development of some types of cancer. PURPOSE: Clinical trial to study the cancer-related genes in patients who have colon cancer or adenomatous polyps.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| cytogenetic analysis | Genetic | — | UNRESOLVED |
| gene mapping | Genetic | — | UNRESOLVED |
| microarray analysis | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Group 1
- description
- Patients donate blood samples for analysis of colorectal susceptibility genes. Patients also complete a questionnaire regarding family cancer history. A certificate of confidentiality protecting the identity of research participants in this project has been issued by the National Cancer Institute. Participants do not receive the results of the genetic testing, and the results do not influence the type or duration of treatment.
- interventionNames
- Genetic: cytogenetic analysis
- Genetic: gene mapping
- Genetic: microarray analysis
Primary outcomes (0)
[]Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 70 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of colon cancer or polyps at age 70 or under * Has a living full sibling with diagnosis of colon cancer or polyps at age 70 or under * No history of familial adenomatous polyposis syndrome * No hereditary nonpolyposis colon cancer, according to Amsterdam criteria * No known I1370K adenomatous polyposis of the colon susceptibility variant * Enrolled on 1 of the following clinical trials: * CLB-9581 * CLB-89803 * CLB-80001 NOTE: Patients do not need to be receiving protocol therapy. Patients who are outside the treatment protocol's follow-up range are eligible. Patients who discontinued therapy for any reason, including toxic effects, are eligible. PATIENT CHARACTERISTICS: Age * 70 and under at diagnosis Other * No significant psychiatric illness that would preclude giving informed consent * No inflammatory bowel disease (in patient or sibling)
References
Publications (0)
Data not yet available
No reference posted for this study.