Clinical trial · Observational
The Sister Study: Genetic and Environmental Risk Factors for Breast Cancer
NCT00047970CI-TRIAL-00017518completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The Sister Study is prospectively examining environmental and familial risk factors for breast cancer and other diseases in a cohort of 50,884 sisters of women who have had breast cancer. Such sisters have about twice the risk of developing breast cancer as other women.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 35 Years
- Maximum age
- 74 Years
Show eligibility criteria text
Inclusion Criteria: Women who are eligible for the Sister Study: * Have a sister (living or deceased) who had breast cancer * Ages 35-74 * Never had breast cancer themselves * Live in the United States The Sister Study is currently recruiting sisters of women diagnosed with breast cancer nationwide.
References
Publications (3)
- DERIVEDO'Brien KM, Sandler DP. Reply to "Vitamin D and breast cancer: Stop torturing the data!". Cancer. 2022 Aug 1;128(15):3000-3001. doi: 10.1002/cncr.34274. Epub 2022 Jun 1. No abstract available. PMID 35647759
- DERIVEDKresovich JK, Park YM, Keller JA, Sandler DP, Taylor JA. Healthy eating patterns and epigenetic measures of biological age. Am J Clin Nutr. 2022 Jan 11;115(1):171-179. doi: 10.1093/ajcn/nqab307. PMID 34637497
- DERIVEDPetimar J, Park YM, Smith-Warner SA, Fung TT, Sandler DP. Dietary index scores and invasive breast cancer risk among women with a family history of breast cancer. Am J Clin Nutr. 2019 May 1;109(5):1393-1401. doi: 10.1093/ajcn/nqy392. PMID 30968114