Clinical trial · Interventional
Acupressure in Treating Nausea in Women Receiving Combination Chemotherapy for Breast Cancer
Treatment of Chemotherapy-Induced Nausea With Acupressure: A Phase III Trial
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Acupressure may help to reduce or prevent nausea in patients who are undergoing chemotherapy. It is not yet known whether acupressure plus standard care for nausea is more effective than standard care alone for nausea in women who are receiving chemotherapy for breast cancer. PURPOSE: Randomized phase III trial to determine the effectiveness of acupressure in treating nausea in women who are receiving combination chemotherapy for breast cancer.
Conditions
Conditions (2)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Breast Cancer | Malignant Breast Neoplasm | CURATED_EXACT | 0.92 |
| Drug-induced Nausea and Vomiting | — | UNRESOLVED | — |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| acupressure therapy | Procedure | — | UNRESOLVED |
| management of therapy complications | Procedure | — | UNRESOLVED |
| nausea and vomiting therapy | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (3)
- type
- EXPERIMENTAL
- label
- Acupressure
- description
- Arm I: Patients receive active acupressure plus usual nausea care during the second or third course of chemotherapy. Acupressure is applied to a specific site each morning and again whenever nausea is experienced for 3-6 minutes.
- interventionNames
- Procedure: acupressure therapy
- Procedure: management of therapy complications
- Procedure: nausea and vomiting therapy
- type
- PLACEBO_COMPARATOR
- label
- Placebo Acupressure
- description
- Arm II: Patients receive placebo acupressure plus usual nausea care during the second or third course of chemotherapy. Acupressure is applied as in arm I except at a non-specific site.
- interventionNames
- Procedure: acupressure therapy
- Procedure: management of therapy complications
- Procedure: nausea and vomiting therapy
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of breast cancer and receiving one of the following combination therapy regimens: * Doxorubicin and cyclophosphamide with or without fluorouracil * Doxorubicin with paclitaxel or docetaxel * Fluorouracil, epirubicin, and cyclophosphamide * Must be beginning second or third course of chemotherapy * Nausea intensity with prior chemotherapy of at least 3 (moderate) on the intensity scale of the Morrow Assessment of Nausea and Emesis * Hormone receptor status: * Not specified PATIENT CHARACTERISTICS: Age * Adult Sex * Female Menopausal status * Not specified Performance status * Not specified Life expectancy * Not specified Hematopoietic * Not specified Hepatic * Not specified Renal * Not specified PRIOR CONCURRENT THERAPY: Biologic therapy * Not specified Chemotherapy * See Disease Characteristics Endocrine therapy * Not specified Radiotherapy * Not specified Surgery * Not specified Other * Concurrent antiemetics allowed
References
Publications (0)
Data not yet available