Clinical trial · Interventional
Marijuana for Cancer Pain
Marijuana in Combination With Opioids for Cancer Pain: A Pilot Study
NCT00046709CI-TRIAL-00012364terminatedPhase 1 / Phase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Discontinued due to non-enrollment.
Summary
Brief summary (as posted)
To find out if it is safe and effective to use smoked marijuana in combination with opioids to treat cancer pain. The study will evaluate whether smoked marijuana, when used with opioids, will have an effect on pain relief, and to see if marijuana reduces the side effects of opioids, which include nausea and/or vomiting.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Neoplasms | Neoplasm | ONTOLOGY_EXACT | 0.90 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Smoked Marijuana | Drug | — | UNRESOLVED |
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- Change in level of cancer pain as recorded on a 100mm Visual Analog Scale.
Secondary outcomes (3)
- measure
- Change in level of experimentally induced pain on a 100mm Visual Analog Scale.
- measure
- Change in nausea and emesis in participants exhibiting these symptoms.
- measure
- Change in disposition kinetics of opioid analgesics.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
INCLUSION CRITERIA * Have ongoing cancer pain * Be diagnosed with cancer and have at least a six month survival. * Be on a stable dose of opioid medication for at least 2 weeks before enrollment. * Have smoked marijuana on at least 6 occasions in their lifetime prior to enrollment. EXCLUSION CRITERIA You must not: * Start chemotherapy, radiation or biphosphonates during the study, or have received any new intervention with any such agents within the past 4 weeks. * Currently be using smoked tobacco products. * Currently be in methadone treatment. * Have smoked marijuana within 30 days of enrollment. * Be diagnosed with diabetes mellitus. * Have severe heart disease, uncontrolled hypertension, or lung disease. * Currently be receiving treatment with corticosteroids. * Be pregnant or breastfeeding.
References
Publications (0)
Data not yet available
No reference posted for this study.