Clinical trial · Interventional
Electroacupuncture in Treating Delayed Nausea and Vomiting in Patients Receiving Chemotherapy For Newly Diagnosed Childhood Sarcoma, Neuroblastoma, Nasopharyngeal Cancer, Germ Cell Tumors, or Hodgkin Lymphoma
A Randomized Study Of Electroacupuncture Treatment For Delayed Chemotherapy-Induced Nausea And Vomiting In Patients With Pediatric Solid Tumors
NCT00040911CI-TRIAL-00010511completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Electroacupuncture may help to reduce or prevent delayed nausea and vomiting in patients treated with chemotherapy. PURPOSE: This randomized clinical trial is studying the effectiveness of electroacupuncture in treating delayed nausea and vomiting in patients who are receiving chemotherapy for newly diagnosed childhood sarcoma, neuroblastoma, nasopharyngeal cancer, germ cell tumors, or Hodgkin lymphoma.
Conditions
Conditions (11)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Brain Tumors | Brain Neoplasm | ALIAS | 0.90 |
| Central Nervous System Tumors | Central Nervous System Neoplasm | ALIAS | 0.90 |
| Childhood Germ Cell Tumor | Childhood Germ Cell Tumor | ONTOLOGY_EXACT | 0.98 |
| Extragonadal Germ Cell Tumor | Extragonadal Germ Cell Tumor | ONTOLOGY_EXACT | 0.98 |
| Head and Neck Cancer | Malignant Head and Neck Neoplasm | ALIAS | 0.90 |
| Lymphoma | Lymphoma | ONTOLOGY_EXACT | 0.90 |
| Nausea | — | UNRESOLVED | — |
| Neuroblastoma | Neuroblastoma |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| electroacupuncture therapy | Procedure | — | UNRESOLVED |
| quality-of-life assessment | Procedure | — | UNRESOLVED |
| sham intervention | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- EXPERIMENTAL
- label
- Arm I (alternative medicine procedure)
- description
- Patients undergo electroacupuncture therapy to specific acupuncture points on the arms and legs over 25 minutes twice daily on days 1 and 2 and then once daily on days 3-7 during week 1 of chemotherapy course 1 (9 acupuncture treatments total).
- interventionNames
- Procedure: electroacupuncture therapy
- Procedure: quality-of-life assessment
- type
- SHAM_COMPARATOR
- label
- Arm II (alternative medicine procedure)
- description
- Patients undergo electroacupuncture therapy to sham points on the arms and legs as in arm I.
- interventionNames
- Procedure: sham intervention
- Procedure: quality-of-life assessment
Primary outcomes (1)
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 5 Years
- Maximum age
- 35 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Newly diagnosed malignancy of 1 of the following types: * Pediatric sarcoma * Neuroblastoma * Nasopharyngeal carcinoma * Germ cell tumor * Hodgkin lymphoma * Meets 1 of the following criteria: * Eligible for Children's Oncology Group (COG) protocol for sarcoma, neuroblastoma, or germ cell tumor * Eligible for NCI Pediatric Oncology Branch (POB) protocol for sarcoma * Following COG-approved standard treatment regimen for sarcoma, neuroblastoma, nasopharyngeal carcinoma, or germ cell tumor * Enrolled on the POB natural history protocol 98-C-0037 * Planned treatment, according to COG or POB protocols, that includes a cisplatin- and/or doxorubicin-containing regimen for sarcoma, neuroblastoma, nasopharyngeal carcinoma, germ cell tumor, or Hodgkin lymphoma OR either a cyclophosphamide/ifosfamide-doxorubicin-containing or cyclophosphamide/dactinomycin-containing regimen for rhabdomyosarcoma * No clinical or radiographic signs of spinal cord compression PATIENT CHARACTERISTICS: Age: * 5 to 35 Performance status: * Not specified Life expectancy: * Not specified Hematopoietic: * Platelet count greater than 50,000/mm\^3 (transfusion independent) * No clotting disorders, including hemophilia Hepatic: * PT and PTT normal (within 10% of institution's upper limit of normal) Renal: * Not specified Other: * Not pregnant * No casting of 1 or more extremities * No other condition that would preclude access to acupuncture points * No cognitive impairment PRIOR CONCURRENT THERAPY: Biologic therapy: * Not specified Chemotherapy: * See Disease Characteristics * No prior systemic chemotherapy Endocrine therapy: * More than 4 weeks since prior glucocorticoid therapy * No concurrent glucocorticoid therapy Radiotherapy: * Not specified Surgery: * Not specified Other: * No prior acupuncture * No concurrent anticoagulants
References
Publications (0)
Data not yet available
No reference posted for this study.