Monoclonal Antibody ABX-EGF in Treating Patients With Renal (Kidney), Prostate, Pancreatic, Non-Small Cell Lung, Colon or Rectal, Esophageal, or Gastroesophageal Junction Cancer

DISEASE CHARACTERISTICS:

* Histologically confirmed diagnosis of 1 of the following:

  * Renal cell cancer (RCC)

    * Prior nephrectomy required
  * Prostate cancer

    * Failed prior primary therapy (e.g., surgery, radiotherapy, or chemotherapy)
    * Failed prior hormonal therapy (e.g., antiandrogen, luteinizing hormone-releasing hormone inhibitor, or orchiectomy)
  * Pancreatic cancer

    * Failed at least 1 prior standard therapy regimen for unresectable metastatic disease
  * Non-small cell lung cancer

    * Failed at least 1 prior standard therapy regimen for unresectable metastatic disease
  * Colorectal cancer

    * Received 1 or more prior chemotherapy regimen(s) for advanced metastatic disease
  * Esophageal cancer

    * Failed prior primary therapy (e.g., surgery, radiotherapy, or chemotherapy)
  * Gastroesophageal junction cancer
* Evaluable disease
* Epidermal growth factor receptor overexpression

  * Tumor tissue must yield the sum of 1+, 2+, or 3+ staining in at least 10% of evaluated tumor cells
* No uncontrolled brain metastases
* No evidence of disease progression or regression after a 30-day washout period

PATIENT CHARACTERISTICS:

Age:

* 18 and over

Performance status:

* Karnofsky 70-100% OR
* ECOG 0-1

Life expectancy:

* Not specified

Hematopoietic:

* Absolute neutrophil count greater than 1,000/mm\^3
* Platelet count greater than 100,000/mm\^3

Hepatic:

* AST/ALT no greater than 2 times upper limit of normal (ULN) (3 times ULN for liver metastases)
* Alkaline phosphatase no greater than 2 times ULN (3 times ULN for liver metastases)

Renal:

* Creatinine less than 2.2 mg/dL
* NCI renal toxicity no greater than grade 2
* No hypercalcemia (antihypercalcemic therapy allowed)

Cardiovascular:

* Ejection fraction at least 45% by MUGA
* No abnormal ECG or MUGA
* No myocardial infarction within the past year

Pulmonary:

* No abnormal chest x-ray
* FEV\_1 greater than 50% of predicted

Other:

* No known allergy to ingredients of study drug
* No known allergy to Staphylococcus aureus Protein A
* HIV negative
* No chronic medical or psychiatric condition that would preclude study compliance
* Not pregnant or nursing
* Negative pregnancy test
* Fertile patients must use effective contraception during and for 2 months after study participation

PRIOR CONCURRENT THERAPY:

Biologic therapy:

* At least 30 days since prior biologic therapy (e.g., antibodies, cytokines, or co-stimulatory pathway inhibitors)
* No other concurrent biologic therapy

Chemotherapy:

* See Disease Characteristics
* At least 6 weeks since prior chemotherapy and recovered
* No prior chemotherapy for RCC
* No prior anthracyclines
* No concurrent chemotherapy

Endocrine therapy:

* See Disease Characteristics
* Concurrent steroids allowed
* Concurrent hormonal therapy allowed

Radiotherapy:

* See Disease Characteristics
* No prior mediastinal radiotherapy
* No concurrent radiotherapy

Surgery:

* See Disease Characteristics
* Recovered from any recent prior surgery

Other:

* At least 30 days since prior investigational drug or device
* At least 30 days since prior systemic therapy
* No other concurrent investigational drugs
* No other concurrent systemic agents or cancer therapy