Clinical trial · Observational
Genetic Study in Patients With Stage II or Stage III Colon Cancer
The Clinical and Pathological Significance of Allelic Imbalance of 8p in Patients With Colorectal Cancer
NCT00003833CI-TRIAL-00023012completedClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Genetic studies may help in understanding the genetic processes that cause some types of cancer. PURPOSE: Genetic trial to study certain genes of patients who have stage II or stage III colon cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colorectal Cancer | Malignant Colorectal Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| DNA stability analysis | Genetic | — | UNRESOLVED |
| gene mapping | Genetic | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- label
- Normal and tumor tissue pairs
- description
- Matched normal and tumor DNA is analyzed for 8p allelic imbalance with at least 8 markers: D8S262 and D8S1825 localized to 8p23, D8S254 and D8S261 at 8p22, D8S560 and D8S136 at 8p21, and D8S1820 and D8S283 at 8p12. Normal/tumor tissue pairs are used for fine mapping studies.
- interventionNames
- Genetic: DNA stability analysis
- Genetic: gene mapping
Primary outcomes (1)
- measure
- overall survival
- timeFrame
- Up to 10 years
Eligibility
Eligibility (as posted)
- Sex
- All
- Maximum age
- 69 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Diagnosis of resectable stage II or III adenocarcinoma of the colon * Participated in NCCTG-914653 * DNA extracted from both normal and tumor tissue PATIENT CHARACTERISTICS: Age * Under 70
References
Publications (0)
Data not yet available
No reference posted for this study.