Clinical trial · Interventional
Radiation Therapy Following Surgery to Remove Brain Metastases
Pilot Study of Adjuvant Fractionated Stereotactic Radiotherapy Following Surgical Removal of Cerebral Metastases
NCT00003320CI-TRIAL-00046381completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Giving radiation therapy after surgery to remove brain metastases may decrease the amount of radiation required to treat brain metastases. PURPOSE: Pilot trial to study the effectiveness of radiation therapy following surgery to remove brain metastases.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Metastatic Cancer | Malignant Neoplasm | CURATED_BROADER | 0.78 |
Interventions
Interventions (3)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| radiation therapy | Radiation | — | UNRESOLVED |
| stereotactic radiosurgery | Radiation | — | UNRESOLVED |
| surgical procedure | Procedure | — | UNRESOLVED |
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Histologically confirmed cerebral metastases post surgical resection * No greater than 3 cerebral metastases postresection * Gross resection at operation as documented in operation note and postoperative MRI Patients must have current surgical sites that have not been previously irradiated * No other indication for whole brain irradiation (i.e., multiple untreated metastases not suitable for single fraction stereotactic radiotherapy, leptomeningeal disease) * Age: 18 and over * Karnofsky 60-100% * Life expectancy: At least 3 months * Prior or concurrent required steroids allowed * Prior stereotactic radiotherapy of cerebral metastases allowed provided no prior irradiation of current surgical sites * Prior surgery of cerebral metastases allowed Exclusion Criteria: * severe asthma requiring therapy * allergy to iodine or contrast media * pregnant * concurrent chemotherapy * prior whole brain irradiation or focal irradiation to current sites of disease
References
Publications (0)
Data not yet available
No reference posted for this study.