Clinical trial · Interventional
SWOG-9430: Surgery in Treating Patients With Metastatic Melanoma
A Phase II Trial of Complete Surgical Resection For Stage IV Melanoma -- Surgical Resection With Biological Evaluation and Clinical Follow-Up
NCT00002860CI-TRIAL-00006058completedPhase 2ClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
RATIONALE: Surgery may be effective therapy in treating patients with metastatic melanoma. PURPOSE: This phase II trial is studying how well surgery works in treating patients with metastatic melanoma.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Melanoma (Skin) | Melanoma | ONTOLOGY_EXACT | 0.85 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Surgery | Procedure | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- surgery
- interventionNames
- Procedure: Surgery
Primary outcomes (1)
- measure
- Overall survival
- timeFrame
- 1-year
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
DISEASE CHARACTERISTICS: * Histologically confirmed metastatic melanoma that is deemed grossly surgically resectable * Multiple resected sites or metastatic melanoma of unknown primary allowed provided all known disease can be grossly resected * Recurrence in iliac lymph nodes after inguinal lymph dissection allowed * No metastatic disease beyond the lesions planned for resection * Confirmed by CT scan of chest, abdomen, pelvis, and CT or MRI of brain within 42 days of study * Concurrent registration on protocol SWOG-9431 required PATIENT CHARACTERISTICS: Age: * 18 and over Performance status: * SWOG 0-2 Hematopoietic: * Not specified Hepatic: * Not specified Renal: * Not specified Other: * No other malignancy within the past 5 years except adequately treated basal cell or squamous cell skin cancer, carcinoma in situ of the cervix, or adequately treated stage I or II cancer from which patient is currently disease free * Not pregnant PRIOR CONCURRENT THERAPY: Biologic therapy: * Prior immunotherapy in the adjuvant or metastatic setting allowed Chemotherapy: * Prior chemotherapy in the adjuvant or metastatic setting allowed Endocrine therapy: * Prior hormonal therapy in the adjuvant or metastatic setting allowed Radiotherapy: * Prior radiotherapy in the adjuvant or metastatic setting allowed Surgery: * See Disease Characteristics * At least 14 days since prior surgery in the adjuvant or metastatic setting Other: * Recovered from prior therapy
References
Publications (1)
- RESULTSondak VK, Liu PY, Warneke J, et al.: Surgical resection for stage IV melanoma: a Southwest Oncology Group trial (S9430). [Abstract] J Clin Oncol 24 (Suppl 18): A-8019, 457s, 2006.