Ranking · Burden

Annual deaths

Number of deaths with this cancer as underlying cause in the reference year for the population scope.

Computedci-mortality-count-v1unit: counthigher = worseAll metrics

Rank	Δ	Cancer	Annual deaths (count)	Percentile	Confidence	Sources	Why #n?
1	=	Malignant Lung Neoplasm	128,663	100	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 4025 siteDefinition USCS "Lung and Bronchus" (ICD-10 C34; ICD-O-3 C340-C349) ranking row 2608813
2	=	Malignant Pancreatic Neoplasm	51,326	96.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 6065 siteDefinition USCS "Pancreas" (ICD-10 C25; ICD-O-3 C250-C259) ranking row 2608814
3	=	Malignant Breast Neoplasm	43,897	93.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 8819 siteDefinition USCS "Male and Female Breast" (ICD-10 C50; ICD-O-3 C500-C509) ranking row 2608815
4	=	Malignant Colon Neoplasm	41,022	90	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 1121 siteDefinition USCS "Colon excluding Rectum" (ICD-10 C18, C26.0; ICD-O-3 C180-C189, C260) ranking row 2608816
5	=	Malignant Prostate Neoplasm	34,815	86.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 8513 siteDefinition USCS "Prostate" (ICD-10 C61; ICD-O-3 C619) ranking row 2608817
6	=	Malignant Liver Neoplasm	30,532	83.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 3719 siteDefinition USCS "Liver and Intrahepatic Bile Duct" (ICD-10 C22; ICD-O-3 C220-C221) ranking row 2608818
7	=	Leukemia	23,903	80	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 3413 siteDefinition USCS "Leukemias" (ICD-10 C91-C95 (leukemia recodes; C90.1 plasma cell leukemia included by SEER); ICD-O-3 leukemia histologies 9733-9948 per SEER site recode) ranking row 2608819
8	=	Non-Hodgkin Lymphoma	19,692	76.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 5555 siteDefinition USCS "Non-Hodgkin Lymphoma" (ICD-10 C82-C85, C96.3; ICD-O-3 histology 9590-9597, 9670-9729, 9735, 9737-9738 (+9811-9818, 9823, 9827, 9837 outside marrow/blood)) ranking row 2608820
9	=	Malignant Central Nervous System Neoplasm	18,523	73.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 611 siteDefinition USCS "Brain and Other Nervous System" (ICD-10 C70, C71, C72; ICD-O-3 C700-C709, C710-C719, C720-C729) ranking row 2608821
10	=	Malignant Bladder Neoplasm	17,396	70	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 7595 siteDefinition USCS "Urinary Bladder" (ICD-10 C67; ICD-O-3 C670-C679) ranking row 2608822
11	=	Malignant Esophageal Neoplasm	16,274	66.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 1631 siteDefinition USCS "Esophagus" (ICD-10 C15; ICD-O-3 C150-C159) ranking row 2608823
12	=	Malignant Kidney Neoplasm	15,214	63.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 2801 siteDefinition USCS "Kidney and Renal Pelvis" (ICD-10 C64-C65; ICD-O-3 C649, C659) ranking row 2608824
13	=	Malignant Rectal Neoplasm	13,446	60	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 6371 siteDefinition USCS "Rectum and Rectosigmoid Junction" (ICD-10 C19-C20; ICD-O-3 C199, C209) ranking row 2608825
14	=	Malignant Ovarian Neoplasm	12,654	56.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 5759 siteDefinition USCS "Ovary" (ICD-10 C56; ICD-O-3 C569) ranking row 2608826
15	=	Multiple Myeloma	11,404	53.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 4943 siteDefinition USCS "Myeloma" (ICD-10 C90.0, C90.2; ICD-O-3 histology 9731-9732, 9734) ranking row 2608827
16	=	Malignant Gastric Neoplasm	11,246	50	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 6983 siteDefinition USCS "Stomach" (ICD-10 C16; ICD-O-3 C160-C169) ranking row 2608828
17	=	Cutaneous Melanoma	8,671	46.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 4331 siteDefinition USCS "Melanomas of the Skin" (ICD-10 C43; ICD-O-3 C440-C449 with histology 8720-8790) ranking row 2608829
18	=	Malignant Uterine Corpus Neoplasm	8,608	43.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 1325 siteDefinition USCS "Corpus" (ICD-10 C54; ICD-O-3 C540-C549) ranking row 2608830
19	▲3	Malignant Cervical Neoplasm	4,207	40	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 815 siteDefinition USCS "Cervix" (ICD-10 C53; ICD-O-3 C530-C539) ranking row 2608831
20	▲3	Malignant Laryngeal Neoplasm	4,095	36.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 3107 siteDefinition USCS "Larynx" (ICD-10 C32; ICD-O-3 C320-C329) ranking row 2608832
21	▲4	Malignant Thyroid Gland Neoplasm	2,229	33.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 7289 siteDefinition USCS "Thyroid" (ICD-10 C73; ICD-O-3 C739) ranking row 2608833
22	▲4	Malignant Mesothelioma	2,114	30	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 4637 siteDefinition USCS "Mesothelioma" (ICD-10 C45; ICD-O-3 histology 9050-9055 (any site)) ranking row 2608834
23	▲4	Malignant Anal Neoplasm	1,650	26.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 305 siteDefinition USCS "Anus, Anal Canal and Anorectum" (ICD-10 C21; ICD-O-3 C210-C212, C218) ranking row 2608835
24	▲4	Malignant Vulvar Neoplasm	1,555	23.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 8003 siteDefinition USCS "Vulva" (ICD-10 C51; ICD-O-3 C510-C519) ranking row 2608836
25	▲4	Malignant Salivary Gland Neoplasm	1,173	20	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 6677 siteDefinition USCS "Salivary Gland" (ICD-10 C07-C08; ICD-O-3 C079-C089) ranking row 2608837
26	▲4	Hodgkin Lymphoma	909	16.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 2039 siteDefinition USCS "Hodgkin Lymphoma" (ICD-10 C81; ICD-O-3 histology 9650-9667 (nodal and extranodal)) ranking row 2608838
27	▲4	Malignant Nasopharyngeal Neoplasm	664	13.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 5249 siteDefinition USCS "Nasopharynx" (ICD-10 C11; ICD-O-3 C110-C119) ranking row 2608839
28	▲4	Malignant Hypopharyngeal Neoplasm	498	10	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 2345 siteDefinition USCS "Hypopharynx" (ICD-10 C12-C13; ICD-O-3 C129, C130-C139) ranking row 2608840
29	▲4	Malignant Testicular Neoplasm	462	6.7	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 8717 siteDefinition USCS "Testis" (ICD-10 C62; ICD-O-3 C620-C629) ranking row 2608841
30	▲4	Malignant Vaginal Neoplasm	435	3.3	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 7799 siteDefinition USCS "Vagina" (ICD-10 C52; ICD-O-3 C529) ranking row 2608842
31	▲4	Malignant Penile Neoplasm	415	0	High confidence	cdc-uscs	inputs sourceId CI-SOURCE-00000012 estimateType observed observationId 8309 siteDefinition USCS "Penis" (ICD-10 C60; ICD-O-3 C600-C609) ranking row 2608843

Data updated 16 hours agoSource updated unknown31 eligible entities · inputs hash eda90f606aa05f603e206877

Methodology

How this table was built

Formula: epidemiology_observations.value WHERE metric = mortality_count
Version: ci-mortality-count-v1
Scope: USA · both sexes · all ages · 2024 · top-level cancers
Scope key: geo=USA|sex=all|age=all|year=2024|level=top
Eligible entities: 31
Generated: Sep 29, 2026, 06:30 AM UTC
Inputs hash: eda90f606aa05f603e206877
Sources: U.S. Cancer Statistics (USCS) — NPCR/SEER incidence and NVSS mortality
Aggregation: none

Eligibility

requires: mortality_count
entityLevel: top

Full methodology · ties share a rank (1, 2, 2, 4) · previous rank refers to the last snapshot of the same scope.

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Burden and lethality metrics depend on registry definitions (site groups, standard population, estimate type). Compare only within one table.

Deadliness annual deaths ≠ age-standardized mortality ≠ mortality-to-incidence ratio ≠ 5-year survival. Each answers a different question.