Publication
Concurrent Antidepressant Use and Metastasis Risk Among Women Receiving Tamoxifen for Breast Cancer: A Real-World Cohort Study.
Shaimaa Elshafie, Mohammed Zuber, Ainhoa Gomez-Lumbreras, Daniel C Malone, Lorenzo Villa Zapata
Psycho-oncologyOct 1, 2026PMID 42814596doi:10.1002/pon.70617 Journal ArticlepubmedProvenance
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- Oct 1, 2026
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- ING-PUBMED-20261001-000001
Abstract
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OBJECTIVE: Concurrent use of antidepressants, particularly cytochrome P450 2D6 (CYP2D6) inhibitors, may reduce tamoxifen bioactivation and effectiveness. However, the clinical significance of this potential interaction remains inconclusive. This study examined whether concurrent antidepressant use…
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- cancerMalignant Breast Neoplasmdictionary0.60
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