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Actinomycin Analogs From Streptomyces polyantibioticus S4D258: Structural Elucidation and Antiproliferative Activity Against Triple-Negative Breast Cancer.

He Pang, Xiao-Min Huang, Usama Ramadan Abdelmohsen, Li Shen, Jun Wu

Chemistry & biodiversityOct 1, 2026PMID 42814512doi:10.1002/cbdv.71791 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Oct 1, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20261001-000001
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Fifteen new actinomycin analogs were obtained from the marine-derived Streptomyces polyantibioticus S4D258. Structural elucidation of these compounds was successfully achieved by comprehensive analysis of high-resolution electrospray ionization mass spectrometry (HR-ESIMS), nuclear magnetic…

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