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Targeting the Epigenetic-Immune Axis in Acute Myeloid Leukemia: Current Advances and Future Directions.

Devangi Ghosh, Mohd Ayoub, Surajit Karmakar, Subhasree Roy Choudhury

Current oncology reportsSep 29, 2026PMID 42809184doi:10.1007/s11912-026-01831-1 Journal ArticleReviewpubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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PURPOSE OF REVIEW: Acute myeloid leukemia (AML) exemplifies how malignant transformation can be driven by both epigenetic deregulation and genetic mutation. Aberrant DNA methylation, histone modifications, and chromatin remodelling cooperate to block myeloid differentiation, sustain leukemic…

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