Publication
SPTLC2-driven sphingolipid reprogramming of neutrophils impairs anti-tumour immunity and drives liver cancer progression.
Zhe Yang, Yun Wang, Jianhao Li, Zishuo Wang, Jianan Chen, Ding Zhang, Guorui Zhao, Liwen Liu, Zhibo Liu, Ning Wang, Ranran Sun
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- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
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Liver cancer exhibits limited and heterogeneous responses to immune checkpoint blockade, underscoring the need to elucidate tumour microenvironmental mechanisms sustaining immune dysfunction. Here, we integrated single-cell transcriptomic annotation with BayesPrism deconvolution across multiple…
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- cancerMalignant Liver Neoplasmdictionary0.60
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