Publication
IL-23-engineered oncolytic vaccinia virus enhances pancreatic cancer control through inflammasome-driven Th17-skewed CD4+ T-cell responses.
Yu Guo, Meng Wang, Yujing Xuan, Lvla Pan, Wenyi Yan, Jisiyu Cheng, Yang Yu, Xiangyu Wang, Lihua Xu, Xianlei Sun, Ruxia Han, Lingling Si, Yaohe Wang, Sirui Li, Pengju Wang
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- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
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BACKGROUND: Oncolytic viruses represent a promising immunotherapeutic strategy for converting pancreatic and other immunologically cold tumors. While their ability to stimulate innate immune signaling and promote antitumor immunity is established, mechanisms enabling durable adaptive responses…
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Candidate 1
- cancerMalignant Pancreatic Neoplasmdictionary0.60
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