Publication
Modulation of intracellular heme metabolism enhances artesunate-induced cytotoxicity in CD44v-positive cervical cancer cells.
Yoko Ueda, Mieko Tsuji, Minako Mori, Ayaka Kusanagi, Kanta Kawai, Tasuku Hirayama, Motoki Takenaka, Noriko Nozawa-Suzuki, Ken-Ichiro Morishige, Hideko Nagasawa, Masanori Isobe
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- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
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In this study, we investigated the role of intracellular heme metabolism in regulating artesunate (ATS)-induced cytotoxicity to overcome therapeutic resistance in refractory cervical cancer. CD44v-positive CaSki cells exhibited resistance to both cisplatin and the ferroptosis inducer erastin,…
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- cancerMalignant Cervical Neoplasmdictionary0.60
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