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Delayed and multisystem immune-related adverse events in MSI-high colon cancer treated with nivolumab plus ipilimumab.

Takato Maeda, Masaki Munakata, Hiroshi Numao, Norihiro Hanabata, Koji Shimaya, Shohei Igarashi, Masayoshi Ko, Yukari Fukutoku, Ryoichi Kikuchi, Hirotake Sakuraba

Clinical journal of gastroenterologySep 28, 2026PMID 42804071doi:10.1007/s12328-026-02460-8 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
Published

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Immune checkpoint inhibitors (ICIs) can cause immune-related adverse events (irAEs) involving multiple organs. However, delayed-onset, multisystem irAEs after treatment discontinuation are uncommon. Here, we present a rare case of a man in his 50s with microsatellite instability-high colon cancer…

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