Publication
Targeted Nanoparticles for PROTAC-Mediated JAK1/JAK2 Degradation for Bladder Cancer Treatment.
Weihong Ding, Xinyue Zhang, Hongdan Wu, Congrui Zhou, Ke Xu, Zongguang Tai, Guowei Xia
International journal of nanomedicineJan 1, 2026PMID 42802799doi:10.2147/IJN.S616713 PMC13616173Journal ArticlepubmedProvenance
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- PubMed
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- Sep 30, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260930-000001
Abstract
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PURPOSE: Although inhibition of the JAK-STAT signaling pathway has shown promise in cancer therapy, the therapeutic potential of PROTAC-mediated JAK1/JAK2 degradation in bladder cancer remains to be fully explored. To improve the delivery and therapeutic efficacy of PROTAC-mediated JAK1/JAK2…
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- cancerMalignant Bladder Neoplasmdictionary0.60
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