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Machine learning-driven M2 macrophage signature for precision prediction of survival and therapy response in acute myeloid leukemia.

Fangmin Zhong, Jing Liu, Jingze Yue, Linlin Zhang, Guangyao Kong

Inflammation research : official journal of the European Histamine Research Society ... [et al.]Sep 27, 2026PMID 42802232doi:10.1007/s00011-026-02379-3 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260929-000001
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BACKGROUND: M2-type tumor-associated macrophages (TAMs) play critical roles in the immunosuppressive microenvironment and treatment resistance of acute myeloid leukemia (AML). However, their single-cell characteristics and predictive value for prognosis and therapy response remain unclear. METHODS:…

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