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A conotoxin-derived peptide exerts anti-tumor effects in ovarian cancer associated with activation of JNK/JunB signaling.

Jiawei Xu, Zihui Chen, Jianda Yue, Na Xiao, Wangfei Xiang, Ying Wang, Zhonghua Liu

Biochemical pharmacologySep 27, 2026PMID 42801994doi:10.1016/j.bcp.2026.118505 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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The discovery of potent anticancer peptides (ACPs) represents a crucial avenue in current targeted tumor therapy. This study systematically evaluated the broad-spectrum antitumor potential of sPep2, a peptide derived from Conus venom. In vitro investigations demonstrated that sPep2 exhibited potent…

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