Publication
Modulating nanoconfined space charge for PCR-free and bisulfite-free detection of cfDNA methylation in ovarian cancer.
Kai Hu, Zimeng Zhang, Bingheng Li, Yalei Gao, Liu Shi, Xuemei Jia
Biosensors & bioelectronicsSep 25, 2026PMID 42801800doi:10.1016/j.bios.2026.119266 Journal ArticlepubmedProvenance
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- Sep 30, 2026
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- ING-PUBMED-20260930-000001
Abstract
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Aberrant DNA methylation in circulating cell-free DNA (cfDNA) represents a critical epigenetic biomarker for noninvasive diagnosis of ovarian cancer. However, conventional methodologies are inherently limited by the destructive nature of bisulfite conversion and the operational complexities of PCR…
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- cancerMalignant Ovarian Neoplasmdictionary0.60
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