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Platycodon grandiflorus-Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis-Driven Membrane Mechanical Remodeling.

Jian Wu, Ruijuan Zhang, Yixin Duan, Shuqi Huo, Xiang Zhang, Yibin Xing, Lingjing Ma, Tiran Jiang, Xingyu Chen, Qingmin Sun

Advanced science (Weinheim, Baden-Wurttemberg, Germany)Sep 27, 2026PMID 42801643doi:10.1002/advs.77900 PMC13616398Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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Plant-derived nanovesicles have emerged as promising natural nanotherapeutics for cancer treatment, yet whether they can overcome the intrinsic resistance of tumor cells to cytotoxic T-cell-mediated killing remains largely unexplored. Here, we show that lipid-enriched Platycodon…

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