Publication
AGK::BRAF fusion activates MAPK signaling, promotes genomic instability, and reduces NIS expression in thyroid cancer cells.
Luiza Sisdelli, Welbert Gomes Rocha, Débora Mota Dias Thomaz, Roxane Hatanaka, Renata Elen Costa da Silva, Guilherme Henrique, Caroline Serrano-Nascimento, Matheus Fabião, Aline Rangel-Pozzo, Sabine Mai, Janete Maria Cerutti
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- PubMed
- Retrieved
- Sep 30, 2026
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- normalized (units and labels harmonized; values unchanged)
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- ING-PUBMED-20260930-000001
Abstract
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The AGK::BRAF fusion is a recurrent oncogenic alteration in sporadic pediatric papillary thyroid carcinoma (PTC), frequently associated with multifocal disease and pulmonary metastasis. However, the molecular and cellular consequences of AGK::BRAF expression in thyroid follicular cells remain…
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Candidate 1
- cancerMalignant Thyroid Gland Neoplasmdictionary0.60
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