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Multi-target blood test for hepatocellular carcinoma early detection: a cross-sectional analysis of the prospective ALTUS study.

Binu V John, Mark Camardo, Amit G Singal, Neehar D Parikh, Ju Dong Yang, Lewis R Roberts, Alvin C Silva, Naga Chalasani, Reena Salgia, John B Kisiel, Kyle Porter, Paul Z Elias, Elle Kielar-Grevstad, Janelle J Bruinsma, Marilyn C Olson, Jorge Garces, Paul J Limburg

Journal of hepatologySep 26, 2026PMID 42800682doi:10.1016/j.jhep.2026.09.011 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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BACKGROUND & AIMS: Globally, 350 million people are at risk for HCC. Ultrasound screening is recommended but is limited by poor early-stage sensitivity and low adherence. This study evaluated whether the multi-target HCC blood test (mt-HBT) demonstrates non-inferior sensitivity for early-stage HCC…

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Registered trialsNCT05064553

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