Publication
Base editing-mediated induction of stop codons in HPV18 E6/E7 for cervical cancer therapy.
Yue Kang, Yifan Wu, Bingting Bao, Xueqian Wang, Zhiqiang Yu, Chen Cao, Zhi Wang, Zhaojie Wang, Gang Chen, Ding Ma, Tao Yi, Zheng Hu, Xun Tian
- Source
- PubMed
- Retrieved
- Sep 30, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-PUBMED-20260930-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Persistent infection with high-risk human papillomaviruses (hrHPVs) is a primary driver of cervical carcinogenesis, with the viral oncogenes E6 and E7 playing pivotal roles. Conventional nuclease-based gene-editing strategies are limited by genome-wide off-target effects and genomic perturbations…
Read on PubMedLinked entities
Linked entities (1)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Candidate 1
- cancerMalignant Cervical Neoplasmdictionary0.60
Curated evidence
Evidence citing this paper (0)
Data not yet available