Publication
The Epigenetic Architecture of Classical Hodgkin Lymphoma: Lineage Erasure, Immune Escape, and Therapeutic Reprogramming.
Matei Seleusan, Diana Cenariu, Adrian-Bogdan Țigu, Diana Gulei, Mădălina Nistor, Ximena Maria Muresan, Mihnea Zdrenghea
Medicina (Kaunas, Lithuania)Sep 9, 2026PMID 42796346doi:10.3390/medicina62091740 PMC13609062Journal ArticleReviewpubmedProvenance
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- Sep 29, 2026
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Abstract
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Classical Hodgkin lymphoma (cHL) is distinguished by a rare population of Hodgkin and Reed-Sternberg (HRS) cells that has largely extinguished its germinal center (GC) B-cell identity while maintaining survival, immune escape, and dependence on a highly organized tumor microenvironment (TME). This…
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- cancerHodgkin Lymphomadictionary0.60
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