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Safety and Feasibility of Endoscopic-Assisted Electrochemotherapy in Addition to Neoadjuvant Treatment of Locally Advanced Rectal Cancer: An Exploratory Randomised Clinical Trial.

Loan Ngo-Stuyt, Rasmus Peuliche Vogelsang, Mustafa Bulut, Helle Hjorth Johannesen, Annika Loft, Malene Broholm, Mikail Gögenur, Adile Orhan, Michael Seiersen, Trine Stigaard, Julie Gehl, Ismail Gögenur

CancersSep 21, 2026PMID 42795032doi:10.3390/cancers18183066 PMC13605616Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260930-000001
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BACKGROUND: Locally advanced rectal cancer (LARC) has high recurrence rates despite aggressive multimodal treatment with neoadjuvant chemoradiotherapy (CRT) followed by surgery. Electrochemotherapy (ECT), combining electroporation with chemotherapy, has shown safety and feasibility in other…

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