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Silymarin and Zinc Oxide Nanoparticles Attenuate Experimental Colon Cancer in Rats Through Crosstalk of miR-192 and β-Catenin Pathways.

Eman H Yousef, Aya Megahed, Alaa Samy, Amgad E Salem, Jawaher Abdullah Alamoudi, Ahmed Abbas, Eman M Embaby

BiomoleculesSep 21, 2026PMID 42793206doi:10.3390/biom16091374 PMC13604585Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 29, 2026
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normalized (units and labels harmonized; values unchanged)
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ING-PUBMED-20260929-000001
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Colon cancer (CC) is a leading cause of cancer-related mortality globally. Although chemotherapy remains the primary treatment, its toxicity and drug resistance highlight the need for alternative therapeutic strategies. Silymarin (Sily), a natural compound, and zinc oxide nanoparticles (ZnO-NPs)…

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