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Neutral Inonotus obliquus polysaccharide (IOP-W): Structural characterization and p53/MAPK-mediated apoptotic activity against pancreatic Cancer unveiled through multi-omics.

Xinze Liu, Guinan Zhu, Lin Wang, Lin Feng, Xin Jin, Jiaqi Zhao, Hongmei Yang, Guangzhe Li, Renbo Tan, Lei Wang, Xilin Wan

International journal of biological macromoleculesSep 25, 2026PMID 42790566doi:10.1016/j.ijbiomac.2026.154618 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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Inonotus obliquus is a medicinal fungus growing on birch bark. A neutral polysaccharide (IOP-W, Mw = 8.222 kDa) was isolated from its crude polysaccharides via sequential DEAE DE-52 cellulose column and Sephadex G-200 gel filtration column chromatography. IOP-W, composed primarily of galactose,…

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