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Overweight BMI compromises survival and correlates with aggressive phenotypes in early-onset but not late-onset rectal cancer patients.

Jinlin Cai, Tuoyang Li, Jingrong Weng, Ziye Zhang, Junyi Han, Ziming Li, Zhihao Xu, Ying Du, Jinxin Lin, Meijin Huang, Xiaolin Wang, Yanxin Luo, Huichuan Yu

The oncologistSep 25, 2026PMID 42789753doi:10.1093/oncolo/oyag380 Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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BACKGROUND: The incidence of early-onset colorectal cancer (EOCRC) is rising globally, presenting unique clinical challenges due to its aggressive nature compared to late-onset cases. While obesity is a known risk factor for carcinogenesis, its prognostic significance specifically on the EOCRC…

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