Publication
Aurora kinase a phosphorylates and stabilizes UHRF1 to maintain DNA methylation and prostate cancer cell survival.
Qin Xiang, Yuchong Peng, Yubing Ye, Xiong Li
EpigeneticsDec 1, 2026PMID 42789740doi:10.1080/15592294.2026.2719245 Journal ArticlepubmedProvenance
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- Sep 29, 2026
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- ING-PUBMED-20260929-000001
Abstract
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Aberrant DNA methylation is a hallmark of prostate cancer (PCa) and plays a critical role in sustaining the epigenetic silencing of tumor suppressor genes. However, how oncogenic signaling pathways interface with the DNA methylation machinery remains poorly understood. In this study, we identify…
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- cancerMalignant Prostate Neoplasmdictionary0.60
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