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BCAM-AKT2 fusion protein promotes unfolded protein response driven oncogenic signaling in SKOV3 epithelial ovarian cancer cell line.

Hala Khazem, Ravid Solomon Zemler, Liron Vardi David, Dvir Reder, Shilhav Meisel Sharon, Shay Hantisteanu, Haim Werner, Ilan Bruchim

PloS oneJan 1, 2026PMID 42789557doi:10.1371/journal.pone.0357882 PMC13614538Journal ArticlepubmedProvenance
Source
PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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In view of the rapidly increasing evidence that gene fusion mutations are frequent drivers of cancer, a deeper understanding of the molecular and functional hallmarks of specific gene fusions in epithelial ovarian cancer (EOC) is essential. In this work we sought to identify the molecular signature…

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