Publication
TGF-β2 promotes autophagy-mediated resistance to doxorubicin in metastatic colon cancer cells via HMGB1.
Sruthi Sritharan, Tamilselvan Jayavelu, Nageswaran Sivalingam
Medical oncology (Northwood, London, England)Sep 25, 2026PMID 42789212doi:10.1007/s12032-026-03404-5 Journal ArticlepubmedProvenance
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- Sep 29, 2026
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Abstract
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Chemoresistance remains a major concern in combating cancer. Colorectal cancer progression is associated with augmented TGF-β serum level. The role of TGF-β2 in promoting doxorubicin resistance in Colo205 cell line was investigated by treating with dox ± TGF-β2 for 7-days. Cell viability,…
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- cancerMalignant Colon Neoplasmdictionary0.60
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