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ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review.

Lucas Oliveira Laurindo, Marjori Lima Boblitz Parente, Greyce Luri Sasahara, João Vitor Caetano Goes, Letícia Rodrigues Sampaio, Yuri Vasconcelos Pinheiro, Ronald Feitosa Pinheiro

Medical oncology (Northwood, London, England)Sep 25, 2026PMID 42789026doi:10.1007/s12032-026-03378-4 PMC13615130Journal ArticleSystematic ReviewpubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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Ataxia Telangiectasia Mutated (ATM), a central kinase in the DNA damage response, is recurrently altered across these disorders, including myelodysplastic neoplasms (MDS), acute myeloid leukemia (AML), and myeloproliferative neoplasms (MPN), yet its clinical significance remains underrecognized. We…

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