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Polyphenol-crosslinked green synthesis of mucoadhesive chitosan nanoparticle encapsulated with cisplatin for localised management of cervical cancer.

Ivy Saha, Tushar Kanti Rajwar, Rakesh Kumar Sahoo, Jitu Halder, Vineet Kumar Rai, Saurjit Mohapatra, Arijit Nandi, Salim Manoharadas, Jameel Al-Tamimi, Biswakanth Kar, Goutam Ghosh, Goutam Rath

Journal of drug targetingSep 29, 2026PMID 42786138doi:10.1080/1061186X.2026.2735993 Journal ArticlepubmedProvenance
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PubMed
Retrieved
Sep 30, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-PUBMED-20260930-000001
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Chitosan (CS) nanoparticles have been widely investigated for cervical cancer (CC) therapy, with tripolyphosphate (TPP) commonly used as a crosslinker. This study explored ellagic acid (EA), a natural polyphenol with anticancer activity, as an alternative crosslinker for cisplatin-loaded…

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